TheraBreath vs. Biotene: A Side-by-Side Mouthwash Comparison

As someone who has experienced dry mouth issues and tried various remedies, I’ve found that both TheraBreath and Biotene are popular market options that have been greatly beneficial. Each product promises to address dry mouth, bad breath, and overall oral health concerns, however, their formulas and effectiveness do vary.

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In this blog post, I aim to provide a detailed comparison of TheraBreath and Biotene, derived from my personal experience. I will be discussing several factors, including their pH levels, cavity prevention, effectiveness against dry mouth, taste, and pricing. My goal is to offer a thorough understanding of each one’s advantages so that you can make an informed decision regarding your oral hygiene routine.


TheraBreath operates on a patented oxygenating formula which features OXYD-8, a type of stabilized chlorine dioxide. This unique formula aids in combating bad breath without causing undesirable side effects, often prevalent with alcohol-based mouthwashes. The TheraBreath Fresh Breath Oral Rinse appreciably includes Xylitol as a sweetener. However, Xylitol is not the only sweetener used; the formula also incorporates Sucralose, an artificial sweetener which does not contribute to tooth decay.

In contrast, the TheraBreath Dry Mouth Oral Rinse only uses Xylitol as a sweetener but includes Glycerin, an element similar to that present in Biotene. Biotene’s formula centers on vegetable glycerin as its main active component, accompanied by Xylitol and Sorbitol sweeteners. Xylitol is a popular choice, but Sorbitol, an artificial sweetener is often avoided by some, as it undergoes some degree of fermentation, unlike Xylitol. However, both rinses are alcohol-free, ensuring suitability for children and those avoiding alcohol.

Packaging and Ease of Use

TheraBreath’s mouthwash is conveniently available in a 16 oz plastic bottle, ideal for regular use. The product includes a small dispenser cup, enhancing its usability. TheraBreath also provides a 3-ounce travel-size version, perfect for those testing the product before committing to a full-size bottle, and an even larger, 1-liter version that is excellent for family use.

Biotene mouthwash comes in three size options: 8 oz, 16 oz, and 33.8 oz. However, the bottle design may not be as user-friendly as TheraBreath’s, as the liquid may squirt out if the bottle is accidentally squeezed when pouring. Additionally, Biotene does not include a dosing cup, which can make it challenging for users to determine how much product to use.

Taste, Flavors, and Mouthfeel

TheraBreath boasts a wide variety of flavors, enhancing versatility and allowing it to be customized to individual preferences. Notably, due to an alcohol-free formula, TheraBreath avoids the common burning sensation experience when swishing.

Biotene, on the other hand, only comes in two flavors: Fresh Mint (blue label) and Gentle Mint (green label). Like TheraBreath, Biotene’s alcohol-free formula ensures no burning sensation during use. However, the flavor of Biotene is weaker and may feel oily in the mouth, while TheraBreath has a strong taste that distracts from any oily mouthfeel.


When it comes to combating dry mouth and bad breath, both TheraBreath and Biotene perform well. TheraBreath Dry Mouth Oral Rinse helps tackle bad breath caused by dry mouth, but it doesn’t contain the patented halitosis-fighting oxygenating compounds found in their Fresh Breath Oral Rinse.

Biotene provides substantial relief from dry mouth but might not be as efficient in overall oral cleaning as TheraBreath Dry Mouth Oral Rinse. I often find myself alternating both – using TheraBreath followed by Biotene – to ensure a comprehensive mouthwashing experience.

Prices and Affordability

Upon comparison, TheraBreath is marginally more expensive, with a 16 oz bottle priced at approximately $9 on their website; although, it can be sourced for less on different online platforms. A standard 33 oz bottle of Biotene is available for around $10, providing substantial value considering the quantity. Biotene offers a reasonable price and a product size that ensures longevity, depending on the frequency of use.

Which Formula Should You Buy?

Choosing between TheraBreath and Biotene largely depends on your specific needs and preferences, as they both perform well in their respective areas.

If your concern is more towards bad breath, TheraBreath Fresh Breath Oral Rinse would be my recommendation. On the other hand, if you are dealing with dry mouth symptoms, TheraBreath Dry Mouth Oral Rinse could be a better option. TheraBreath even provides lozenges which can further help alleviate dry mouth symptoms.

Biotene, with its primary active ingredient being vegetable glycerin, also promises relief from a dry mouth – making it an excellent night-time rinse, and particularly beneficial when visiting very dry climates.

While both TheraBreath and Biotene are ADA-accepted, they differ in the level of alkalinity offered. TheraBreath holds the higher ground with a pH of 9.82, providing an environment where cavity-causing bacteria find it hard to thrive. Nonetheless, Biotene’s pH of 6.63 also protects against cavities as it is above the critical pH level of 5.5.

In terms of texture and taste, TheraBreath is generally preferred due to its robust flavor effectively masking any oily sensation. Biotene, on the other hand, has a milder mint taste with a slightly oilier texture. Despite this, Biotene excels at moisturizing the mouth but lacks behind TheraBreath in overall cleansing power.

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However, keep in mind that these mouthwashes are not a substitute for proper oral hygiene. Regular brushing and flossing are still key to maintaining oral health.

Final Thoughts

Both TheraBreath and Biotene have their unique strengths. TheraBreath surpasses Biotene in offering a flavor variety, user-friendly packaging, and increased alkalinity. On the other hand, Biotene excels in its affordability and generous product size. It’s important that your individual oral health needs guide your choice.

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Nonetheless, both TheraBreath and Biotene come highly recommended for those dealing with chronic dry mouth, including conditions like Sjögren’s syndrome, provided they are used as part of a regular oral hygiene routine, which includes brushing and flossing. Maintaining such a routine is essential for long-term oral health, and the use of a good mouthwash simply provides an additional layer of protection and freshness.

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